临床神经病学杂志2012，Vol.25Issue(5)：321-324,4.
同步EEG-功能性MRI对颞叶癫痫致痫灶的定位作用
Effects of localization of simultaneous EEG-functional MRI on epileptogenic focus in temporal lobe epilepsy
摘要
Abstract
Objective To explore the effects of localization of simultaneous EEG-functional MRI (fMRI) on epileptogenic focus in temporal lobe epilepsy. Methods Seventeen patients with symptomatic temporal lobe epilepsy -twere examined by simultaneous EEG-fMRI. The fMRI data collected during the time at epileptic discharge were analysed, and the area where the blood oxygen level-dependent signal changed by epileptic discharge was overlaid onto the image of MRI, then the localization of epileptogenic focus could be identified. Furthermore, the localization was compared with which described by intraoperative electrocorticography (ECoG) and deep electrodes. Results The activated regions in simultaneous EEG-fMRI were completely consistent with epileptogenic focus described by intraoperative ECoG and deep electrodes in 10 cases. Another 7 cases had a consistent central position with ECoG and deep electrodes, but the range was larger at simultaneous EEG-fMRI. Seizure of 14 patients was controled, and the seizure rate of the other 3 patients was obviously decreased after operation. Conclusion Simultaneous EEG-fMRI is accurate and noninvasive to localize the epileptogenic focus in temporal lobe epilepsy, which has reliabe guidance effect for the localization of operation.关键词
颞叶癫痫/同步EEG-功能性MRI/致痫灶/定位Key words
temporal lobe epilepsy/ simultaneous EEG-fMRI/ epileptogenic focus/ localization分类
医药卫生引用本文复制引用
钱若兵,傅先明,魏祥品,林彬,季学兵,刘向,牛朝诗,汪业汉..同步EEG-功能性MRI对颞叶癫痫致痫灶的定位作用[J].临床神经病学杂志,2012,25(5):321-324,4.基金项目
安徽省高校省级自然科学研究项目(KJ2010B377) （KJ2010B377）
安徽省卫生厅医学科研课题(09A056) （09A056）
