临床神经病学杂志2012，Vol.25Issue(5)：373-374,2.
蛛网膜下腔出血后迟发性脑缺血患者血清可溶性凝集素样氧化型低密度脂蛋白受体-1水平的变化及其意义
Change and its significance of serum soluble lectin-like oxidized low-density lipoprotein receptor-1 levels in patients with delayed cerebral ischemia after subarachnoid hemorrhage
郝彩江 1毓青2
作者信息
- 1. 300350 天津市海河医院脑系科
- 2. 天津医科大学总医院神经内科
- 折叠
摘要
Abstract
Objective To study the change and its significance of serum soluble lectin-like oxidized low-density lipoprotein receptor-1 (sLOX-1) levels in patients with delayed cerebral ischemia ( DCI) after subarachnoid hemorrhage ( SAH). Methods According to whether DCI happened, 132 SAH patients were divided into DCI group ^34 cases) and non-DCI group (98 cases). Serum sLOX-1 levels of the patients were measured by enzyme-linked immunosorbent assay kits, and the results were analyzed. Results The serum sLOX-1 levels in DCI group [1325 (313 -2698) pg/ml] were significantly higher than that in non-DCI group [757 ( 128 - 1762) pg/ml] (P <0. 01). Logistic analysis showed that the increase of serum sLOX-1 level was the independent risk factor of DCI in SAH patients (Oft=2.362, 95%C/: 1.276-3.707, P < 0. 05). Conclusions The increase of serum sLOX-1 level can be a useful serum biomarker to predict DCI in SAH patients.关键词
可溶性凝集素样氧化型低密度脂蛋白受体-1/蛛网膜下腔出血/迟发性脑缺血Key words
soluble lectin-like oxidized low-density lipoprotein receptor-1/ subarachnoid hemorrhage/ delayed cerebral ischemia分类
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郝彩江,毓青..蛛网膜下腔出血后迟发性脑缺血患者血清可溶性凝集素样氧化型低密度脂蛋白受体-1水平的变化及其意义[J].临床神经病学杂志,2012,25(5):373-374,2.
