临床神经病学杂志2012，Vol.25Issue(5)：383-384,2.
急性脑梗死患者血清脂蛋白(a)、超敏C反应蛋白水平的改变及其临床意义
Changes and its clinical significance of serum levels of lipoprotein(a), high sensitivity C-reactive protein in patients with acute cerebral infarction
王峥 1陈伟贤 1陆小伟 1曾彦英 1段丽敏1
作者信息
- 1. 210029 南京医科大学第一附属医院老年医学科
- 折叠
摘要
Abstract
Objective To explore the changes and its clinical significance of serum levels of lipoprotein (a) [Lp(a)] , high sensitivity C-reactive protein(hs-CRP) in patients with acute cerebral infarction (ACI). Methods The levels of serum Lp(a) and hs-CRP in 101 ACI patients and 40 normal controls( NC group) were examined by immune-turbidimetry and immune scatter turbidimetry. ACI patients were assessed by national institutes of health stroke scale (NIHSS). The levels of serum Lp (a) and hs-CRP were compared among the patients with different NIHSS score. The relationship between levels of serum Lp(a) and hs-CRP was analyzed. Results The levels of serum Lp (a) and hs-CRP in ACI group were significant higher than those in NC group (all P <0.05 ). The differences of serum levels of Lp(a) and hs-CRP were statistical significance among NIHSS <5,5 ~ 15 and > 15 score sub-groups (all P<0.05). The higher scores of NIHSS, the higher of the serum levels of Lp (a) and hs-CRP. The serum level of Lp (a) was positively related with hs-CRP (r=0.457,P<0.05). Conclusions The levels of serum Lp(a) and hs-CRP are signficantly elevated in ACI patients. Lp(a) and hs-CRP may have cooperative action in ACI onset.关键词
急性脑梗死/脂蛋白(a)/超敏C反应蛋白Key words
acute cerebral ischemic/ lipoprotein(a) / high sensitivity C-reactive protein分类
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王峥,陈伟贤,陆小伟,曾彦英,段丽敏..急性脑梗死患者血清脂蛋白(a)、超敏C反应蛋白水平的改变及其临床意义[J].临床神经病学杂志,2012,25(5):383-384,2.
