临床神经病学杂志2012,Vol.25Issue(6):449-451,3.
腔隙性脑梗死患者卒中后抑郁的临床分析
Clinical analyses of post-stroke depression in patients with lacunar infarction
张君 1陈春富 1王维 1李继川 1郁飞宇1
作者信息
- 1. 250021济南,山东大学附属省立医院神经内科
- 折叠
摘要
Abstract
Objective To explore the characteristics and related factors of post-stroke depression (PSD) in patients with lacunar infarction (LI). Methods One hundred and thirty-eight LI patients confirmed with CT or MRI, were evaluated by Hamilton depression rating scale (HAMD) and Selfrating depression scale (SDS) ,and divided into PSD group and non-PSD group. The influence factors on PSD including infarct lesion location and quantity, the patients' age, education, neurological deficits score and combined disease were analyzed. Results In this group, the incidence of PSD was 31. 2% (43 cases). Mostly of the depression was slightly and the main performance was anxiety/somatization. Compared with non-PSD group, the ratio of ≥65 year old, the lower education level, combined hypertension and neurological deficits score in PSD group were significantly higher (P < 0. 01 - 0. 001). The neurological deficits score was positive correlated with PSD(r =0. 988 ,P <0. 01). PSD ratio in patients with multiple infarct lesions or which located in the thalamus, caudate nucleus, lenticular nucleus were significantly higher than the patients with single infarct lesion or which located in subcortical white matter (all P < 0. 01). Conclusion PSD in LI patients mostly is slight. The common symptoms are anxiety/somatization. PSD may be associated with psychological biological-social factors, such as lesion location, condition of illness, education level and so on.关键词
腔隙性脑梗死/卒中后抑郁Key words
lacunar cerebral infarcts/ post-storke depression分类
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张君,陈春富,王维,李继川,郁飞宇..腔隙性脑梗死患者卒中后抑郁的临床分析[J].临床神经病学杂志,2012,25(6):449-451,3.