临床神经病学杂志2012，Vol.25Issue(6)：461-462,2.
脑膜癌病的临床特点
Clinical features of meningeal carcinomatosis
管青山 1张丽 1靳凌 1胡秀秀 1王小姗1
作者信息
- 1. 210029 南京医科大学附属脑科医院神经内科
- 折叠
摘要
Abstract
Objective To discuss the clinical features of meningeal carcinomatosis (MC). Methods The clinical data of 25 MC patients were analyzed retrospectively. Results In this group, there were 7 cases with malignant tumor history. The clinical manifestations were headache in 24 cases, nausea and vomiting in 21 cases, disturbance of consciousness and limb weakness in 6 cases respectively; seizures, mental symptoms and hypopsia in 5 cases respectively, etc. The positive meningeal irritation was in 20 cases, papilledema was in 12 cases. The CSF pressure was increased in 13 cases, the level of CSF protein was increased in 16 cases, glucose and chlorine were decreased in 14 cases. The tumor cells were found out in 23 cases by CSF cytological examination; while, the immunohistochemical staining was positive in 17 cases. The skull MRI scan were not found meningeal abnormal signal. The meningeal enhancement was found out in 2 of 5 cases by MRI enhanced scan. Conclusions The main clinical manifestation of MC is intracranial hypertension sympotem group. CSF cytological examination and immunohistochemical staining can make diagnosis and fount out the source of cancer cells.关键词
脑膜癌病/临床特点/CSF细胞学Key words
meningeal carcinomatosis/ clinical feature/ cerebrospinal fluid cytology分类
医药卫生引用本文复制引用
管青山,张丽,靳凌,胡秀秀,王小姗..脑膜癌病的临床特点[J].临床神经病学杂志,2012,25(6):461-462,2.
