临床神经外科杂志2012，Vol.9Issue(6)：346-348,3.DOI:10.3969/j.issn.1672-7770.2012.06.009
立体定向海马杏仁核复合体毁损术治疗MRI阴性与MRI阳性颞叶癫(癎)疗效的差异
Difference in therapeutic efficacy about RF-thermocoagulation of amygdala-hippocampus complex in stereotactic surgery for intractable MRI-negative and MRI-positive temporal lobe epilepsy
摘要
Abstract
Objective To evaluate therapeutic efficacy of deep-brain electrode-guided stereotactic surgery for intractable MRI-negative and MRI-positive temporal lobe epilepsy. Methods 256 patients with temporal lobe epilepsy were treated with deep-brain electrode-guided stereotactic RF-thermocoagulation of amygdala-hippocampus complex. 127 of them were followed-up according to Engel standard of curative effect, then divided into MRI-negative and MRI-positive groups to figure out the difference in therapeutic efficacy. Results The followed up time was 2-70 months. There was Engell in 41 patients, EngelⅡin 7, Engel Ⅲ in 22, and Engel Ⅳ in 57. MRI-negative group completely control of seizures were achieved in 50% ; MRI-positive group completely control of seizures were only achieved in 16%. There was significant difference in therapeutic efficacy (X2 = 16.33,P ＜ 0.005). Conclusion Choosing MRI-negative patients to operative are the key factors to improve the therapeutic efficacy of stereotactic RF-thermo-coagulation surgery for temporal lobe epilepsy.关键词
颞叶癫(癎)/深部脑电记录电极/立体定向Key words
temporal lobe epilepsy/ deep-brain electrode/ stereotactic techniques分类
医药卫生引用本文复制引用
罗惠民,刘青,赵全军,林鸿,吴朝辉,田增民,张剑宁,王红,王福莉,李红玉..立体定向海马杏仁核复合体毁损术治疗MRI阴性与MRI阳性颞叶癫(癎)疗效的差异[J].临床神经外科杂志,2012,9(6):346-348,3.基金项目
首都临床特色研究基金项目(Z111107058811018) （Z111107058811018）
