临床神经外科杂志2012，Vol.9Issue(6)：352-354,3.DOI:10.3969/j.issn.1672-7770.2012.06.011
影响正常压力性脑积水分流术的预后因素
Analysis of prognostic factors for cerebrospinal fluid shunt in patients with normal pressure hydrocephalus
王永谦 1王维平 1于明琨2
作者信息
- 1. 200032 上海中医药大学附属龙华医院神经外科
- 2. 上海第二军医大学附属长征医院神经外科
- 折叠
摘要
Abstract
Objective To evaluate the factors influencing the shunt of normal pressure hydrocephalus (NPH). Methods The efficacy of shunt was analyzed according to the clinical symptoms, causes of disease, duration, cerebrospinal fluid (CSF) tap test and CSF external lumbar drainage test. Results Among the 27 shunted patients, 7 had a very good outcome, 15 had a good outcome, and 4 had a poor outcome three month after shunt implantation. Patients with gait disturbance had excellent improvement of their clinical signs whereas patients with dementia and urinary incontinence had a gradual improvement after surgical intervention. Patients with an opening CSF pressure over 140 mmH2O following lumbar puncture showed a statistically significant better outcome than those with an opening pressure below 140 mmH2O. Only twenty-five percent of the patients with an pulsatile pressure below 140 mmH2O and volume of CSF drainage short of 150 ml during over-night monitoring (8p. m. to 8 a. m. ) were poor responders. Conclusion The results of the clinical examination and CSF dynamics serve as decision aids for predicting the outcome after CSF shunting in NPH patients.关键词
正常压力脑积水/分流手术/预后Key words
normal-pressure hydrocephalus/ shunt operation/ prognosis分类
医药卫生引用本文复制引用
王永谦,王维平,于明琨..影响正常压力性脑积水分流术的预后因素[J].临床神经外科杂志,2012,9(6):352-354,3.
