天津中医药2012，Vol.29Issue(6)：534-537,4.
扶正合剂联合化疗治疗老年晚期非小细胞肺癌疗效观察
Effect of Fuzheng mistura combined with chemotherapy on patients with non-small cell lung cancer in senile advanced stage
摘要
Abstract
[Objective] To observe the effect and side reaction of Fuzheng mistura combined with GP scheme chemotherapy on patients with non-small cell lung cancer in senile advanced stage. [Methods] Fifty patients with confirmed diagnosis of advanced non-small cell lung cancer were enrolled. They were randomly divided into two groups. Group A was given with gemcitabine plus carboplatin solution chemotherapy intravenously, and group B with Fuzheng mistura orally. Twenty-eight days was a course and the treatment was continuously used for two chemotherapy courses. [Results] Fuzheng mistura in chemotherapy of older patients with advanced non small cell lung cancer had a therapeutic effect. In decreasing the cancer size the clinical benefit rate of group B was better than that of group A with significant difference (P<0.05). In reducing the serum tumor markers, the change of CEA level had significant difference (P<0.05) of both groups before and after treatment. There was no statistical difference in CYFRA-21 level (P>0.05). There was significant difference (P< 0.05) between two groups of patients in the improvement of immune function, casparian score, clinical symptoms. A significant differences were also found in side reactions, nausea vomiting, decreasing of leucocyte count. Their incidence in group B was lower than that in group A. [Conclusion] Fuzheng mistura has effect-increasing and detoxification effect in chemotherapy in older patients with advanced non small cell lung cancer.关键词
扶正合剂/非小细胞肺癌/老年/化疗Key words
Fuzheng mistura/ non-small cell lung cancer/ older patient/ chemotherapy分类
医药卫生引用本文复制引用
张莹,贾英杰,陈军,孙一予,李小江..扶正合剂联合化疗治疗老年晚期非小细胞肺癌疗效观察[J].天津中医药,2012,29(6):534-537,4.基金项目
天津市应用基础及前沿技术研究计划(青年基金项目)12JCQNJC07500. （青年基金项目）
