天津中医药2012，Vol.29Issue(6)：566-569,4.
复健片对MCAO大鼠脑梗死周围组织RhoA表达的影响
Effect of Fujian tablet on expression of RhoA in rats with cerebral infarction
摘要
Abstract
[Objective] To explore the mechanism of Fujian tablet for promoting neural regeneration by observing the effect of Fujian tablet on the expression of RhoA in rats with cerebral infarction. [Methods] Sixty SD rats were randomly divided into normal control, sham operation, model and medicine groups. The rat model with middle cerebral artery occlusion was successfully established by the improved method of Longa EZ. The treatment groups were given with Fujian tablet, other groups with a identical amount of distilled water. The expressions of RhoA in the region around the infarction were observed by immunohistochemical method. [Results] The difference of RhoA expression between medicine group and model group was significant (P<0.05). [Conclusion] The Fujian tablet can promote neurogenesis by inhibiting the expression of RhoA.关键词
复健片/脑梗死/神经再生/抑制因子/RhoAKey words
Fujian tablet/ cerebral infarction/ neural regeneration/ inhibiting factor/ RhoA分类
医药卫生引用本文复制引用
胡怀强,周永红,王树才,曹秉振..复健片对MCAO大鼠脑梗死周围组织RhoA表达的影响[J].天津中医药,2012,29(6):566-569,4.基金项目
国家自然科学基金资助项目(81001591),山东省自然科学基金资助项目(ZR2010HQ065). （81001591）
