西南国防医药2012，Vol.22Issue(12)：1304-1306,3.DOI:10.3969/j.issn.1004-0188.2012.12.011
雷替曲塞联合微波消融治疗结直肠癌肝转移18例
Treatment of colorectal cancer with hepatic metastasis by raltitrexed combined with percutaneous microwave coagulation therapy in 18 cases
陈滔 1程朋 1李东 1苏晓妹 1刘明昌 1李焱 1杨波 1张涛1
作者信息
- 1. 610083成都,成都军区总医院肿瘤诊治中心
- 折叠
摘要
Abstract
Objective To observe the therapeutic effects of raltitrexed combined with percutaneous microwave coagulation therapy (PMCT) on colorectal cancer with hepatic metastasis. Methods Raltitrexed combined with PMCT was used in the treatment of 18 patients with colorectal cancer and hepatic metastasis who could not receive excision, did not agree to receive the targeted therapy and whose tumors appeared progressive under the treatment of FOLFOX or FOLFIRI. Results After the treatment, complete tumor necrosis was observed in 36 focuses of totally 42 focuses in the 18 patients, and partial necrosis was observed in another 6 focuses. PMCT was performed once again on those 6 focuses with partial necrosis which completely necrosed after the operation. During the follow - up, new focuses were found in 3 cases that included one case of extrahepatic metastasis and two ones of intrahepatic metastasis. The middle survival time (MST) was 26 months. The one - year and two - year survival rates were 83.3% and 66.7% , respectively. Conclusion The treatment of colorectal cancer with hepatic metastasis by rallitrexed combined with percutaneous microwave coagulation is safe and effective. Further exploration and research are worthwhile.关键词
雷替曲塞/微波消融/结直肠癌/肝转移Key words
raltitrexed/ percutaneous microwave coagulation therapy/ colorectal cancer/ hepatic metastasis分类
医药卫生引用本文复制引用
陈滔,程朋,李东,苏晓妹,刘明昌,李焱,杨波,张涛..雷替曲塞联合微波消融治疗结直肠癌肝转移18例[J].西南国防医药,2012,22(12):1304-1306,3.
