中国当代儿科杂志2012，Vol.14Issue(11)：827-829,3.
婴幼儿社区获得性肺炎克雷伯菌肺炎的临床特点及耐药分析
Clinical features and antimicrobial resistance of community-acquired pneumonia caused by Klebsiella pneumoniae in infants
何丽芸 1王应建 1李季美1
作者信息
- 1. 昆明市妇幼保健院儿科,云南 昆明 650031
- 折叠
摘要
Abstract
Objective To study the clinical features and antimicrobial resistance of community-acquired pneumonia caused by Klebsiella pneumoniae in infants. Methods The clinical data of 65 infants with community-acquired pneumonia caused by Klebsiella pneumoniae between 2007 and 2011 were retrospectively studied. Results Of the 65 infants, 37 cases (57% ) were aged ≤ 3 months, 17 cases (26% ) over 4 months, 7 cases (11%) over 7 months and 4 cases (6% ) between 13 and 24 months. There were no significant differences in clinical manifestations and chest X-ray features between the infants with community-acquired pneumonia caused by Klebsiella pneumoniae and those with other bacterial pneumonia. Forty strains (62% ) of ESBLs-producing Klebsiella pneumoniae were detected. Klebsiella pneumoniae was 100% sensitive to imipenem, meropenem and amikacin but resistant to penicillins and cephalosporins. The resistance rates of ESBLs-producing strains to penicillins, cephalosporins, amoxicillin/clavulanic acid, ampicillin/sulbactam, compound sulfamethoxazole, gentamycin, ciprofloxacin and aztreonam were significantly higher than for non-ESBLs-producing strains. ESBLs-producing strains also showed multiple-drug resistance. Conclusions Community-acquired pneumonia caused by Klebsiella pneumoniae is common in infants aged ≤ 3 months. ESBLs-producing strains are prevalent in community-acquired pneumonia caused by Klebsiella pneumoniae and demonstrate both high rates of drug resistance and multiple-drug resistance.关键词
社区获得性肺炎/肺炎克雷伯菌/耐药性/婴幼儿Key words
Community-acquired pneumonia/Klebsiella pneumoniae/Drug resistance/Infant分类
医药卫生引用本文复制引用
何丽芸,王应建,李季美..婴幼儿社区获得性肺炎克雷伯菌肺炎的临床特点及耐药分析[J].中国当代儿科杂志,2012,14(11):827-829,3.
