中国动脉硬化杂志2012，Vol.20Issue(11)：1021-1024,4.
脑梗死合并代谢综合征患者脂联素水平与代谢紊乱的关系
The Analysis of the Relationship Between Adiponectin and Metabolic Abnormalities in Patients with Acute Cerebral Infarction Complicated by Metabolic Syndrome
朱立勋 1陆学胜 1丁素菊2
作者信息
- 1. 上海长宁区中心医院神经内科,上海市200336
- 2. 第二军医大学附属长海医院,上海市200433
- 折叠
摘要
Abstract
Aim To investigate the relationship between adiponectin and metabolic abnormalities in patients with acute cerebral infarction complicated by metabolic syndrome (MS). Methods 74 hospitalized patients with acute is-chemic stroke were studied. All subjects were divided into MS group and non MS group with the criteria of MS published by international diabetes federation (IDF). For patient with MS, we divided it into three MS components group and four or five MS components group. The level of plasma adiponectin and serum TC, TG, LDL, HDL were detected by EILSA technology and the relationship between adiponectin and serum TC,TG, LDL,HDL were examined by Multiple linear regression analysis. Results The patients with acute cerebral infarction complicated by MS showed lower levels of plasma adiponectin and higher levels of serum TG compared with control group (P < 0. 05). In four or five MS components group, the value of plasma adiponectin decreased obviously compared with control group and the levels of Serum TG, TC, LDL and HDL increased or decreased compared with control group (f<0. 05). The result of Multiple linear regression analysis indicated that the levels of plasma adiponectin was significantly associated with TG inversely (b = - 1. 089,b' = - 0. 317, P = 0. 002). Conclusions The value of plasma adiponectin in patients decreased obviously compared with control group. Plasma adiponectin was significantly associated with TG.关键词
脂联素/代谢综合征/急性脑梗死/危险因素Key words
Adiponectin/ Metabolic Syndrome/ Acute Cerebral Infarction/ Risk Factor分类
医药卫生引用本文复制引用
朱立勋,陆学胜,丁素菊..脑梗死合并代谢综合征患者脂联素水平与代谢紊乱的关系[J].中国动脉硬化杂志,2012,20(11):1021-1024,4.
