中国实用儿科杂志2012，Vol.27Issue(11)：834-839,6.
急性呼吸道感染8172例住院患儿病原学分析
Etiologic analysis of 8172 cases of acute respiratory cract infection in hospitalized children
摘要
Abstract
Objective To investigate etiology of acute respiratory infection in hospitalized children. Methods From Oct 2005 to Sep 2009, 8172 hospitalized children with ARI were chosen, of which 6599 cases were detected seven common viruses antigen and hMPV gene using direct immunofluorescence and RT-PCR, 6404 specimens were cultured for bacteria; 7842 cases were detected the antibodies against MP by ELISA. Then analyze and study the positive cases. Results The positive specimens of one or more pathogens detected were 4756(58.2%) of 8172 cases.Bacterial infections were 1883(29.4%) in 6404 cases. Viral infections were 1886(28.2%) in 6599 cases. Mycoplasma pneumoniae were 2630(33.5%) in 7842 cases. The top four of bacterial detection rate were SP(10.8%), HI(4.8%) ,SA(4.7%) and MC (3.4%) ; the top four of virus detection rate were RSV(15.8%) ,hMPV(8.3%) ,PIV-3(2.1%) and IVA (2.0%). Pathogen mixed infection rate was 16.9%; virus mixed with bacteria infection was the most common, detection rate of o ~ ly group were highest for the SP, HI, SA, RSV and PIV-3, higher detection rate in 3 ~ 5y for hMPV, higher in 3 ~ 5y and > 5y for MP. In terms of seasonal distribution, detection rate of bacteria was lowest in autumn, no difference between the other three seasons; detection rate of RSV was higher in winter and spring, hMPV higher in winter and spring, PIV-3 higher in summer, IVA lower in summer; detection rate of MP was higher in summer and autumn. Conclusion MP is the most common important pathogen of children ARI in local area, followed by viruses; bacteria was the most common in mixed infections. The most common pathogens of bacteria and virus are SP, HI, SA, MC and RSV, hMPV, PIV-3, respectively. Virus and bacteria infection is more common in infants less than 1 year. Mycoplasma pneumoniae infection is more common in children older than 3 years.关键词
呼吸道感染/儿童/病原Key words
respiratory tract infection/children/pathogen分类
医药卫生引用本文复制引用
王宇清,季伟,陈正荣,严永东,周卫芳,郭红波..急性呼吸道感染8172例住院患儿病原学分析[J].中国实用儿科杂志,2012,27(11):834-839,6.基金项目
苏州市"科教兴卫"青年科技项目(项目编号:NO.SWKQ1021) （项目编号:NO.SWKQ1021）
