摘要
Abstract
Since encephalitis associated with antibodies against neuronal cell surface antigens hasn't been known enough by people,it has always been delayed diagnosis and treatment,which results in an adverse effect on its prognosis. The target antigens of encephalitis associated with antibodies against neuronal cell surface antigens play an important role in synaptic transmission,plasticity and nerve excitability,including NMDAR,AMPAR,GABABR and other receptors such as LG11 and Caspr2. This kind of disease mainly occurs in children and young people and has relatively severe disease degree and longer disease course,with or without tumor,which has a relatively good prognosis after treatment but has a trend of recurrence. In this study,the introduction of clinical characteristics and the update of diagnosis and treatment were highlighted so as to cause the concerns of clinicians.关键词
神经元表面抗原抗体/AMPA受体/NMDA受体/GABAB受体/LGI1/Caspr2Key words
antibody against neuronal cell surface antigen/ the AMPA receptor/ the NMDA receptor/ CAB AB receptor /leucin-erich glioma-inactivated 1 /contactin-associated protein-like 2分类
医药卫生