摘要
Abstract
Objective To explore the gender difference of prognosis in patients with ST-segment elevation myocardial infarction ( STEMI) undergoing primary percutaneous coronary intervention ( pPCI) . Methods Between April 2003 and March 2009,743 patients undergoing pPCI in Beijing Friendship Hospital Affiliated to Capital Medical University due to STEMI were collected and compared their ( male:n = 558 ; female; n = 185 ) risk factors, characteristics of coronary anqioqraphy and prognosis. Multivariate analysis was performed for risk factors predicting one-year death. Results Compared with male group, female group was much older. More female patients had combined hypertension and diabetes, myocardial infarction (MI) history,longer perfusion and worse hospitalized heart functions (P<0. 05). Furthermore,female patients had higher multi-vessel lesion ratios but lower use rates of β receptor blocker and ACEI or ARB than male patients. Major adverse cardiovascular event (MACE) in female group was significantly higher than that in male group (P <0. 05) in hospital. And MACE and mortality in female group were obviously higher than those in male group (P < 0. 05). Multivariate logistic regression analysis showed that age, diabetes, multi-vessel lesion, delayed reperfusion, the use rates of (3 receptor blocker and ACEI/ARB were independent risk factors to affect pPCI treatment for patients with STEMI (P <0. 05). While the age,hypertension and heart function did not enter logistic regression equation. Conclusion The prognosis of female patients undergoing pPCI was worse than that of male patients during hospitalization and 1 year after pPCI, and complicated with more complications in puncture region,which might be correlated with older age,more complications,worse heart function,delayed reperfusion, and lower use rates of (3 receptor blocker and ACEI or ARB of female patients.关键词
ST段抬高/心肌梗死/经皮冠状动脉介入治疗Key words
ST-segment/elevation myocardial infarction/primary percutaneous coronary intervention分类
医药卫生
