中国实用内科杂志2012，Vol.32Issue(12)：928-931,4.
KDIGO指南解读:特发性膜性肾病治疗
Treatment of idiopathic membranous nephropathy:interpretation of KDIGO guideline
邢昌赢1
作者信息
- 1. 南京医科大学第一附属医院肾内科,南京210029
- 折叠
摘要
Abstract
The diagnosis of idiopathic membranous nephrology ( IMN) ,a common pathological subtype of nephrotic syndrome in adults,has been established via renal biopsy and excluding secondary membranous nephrology. The standardized treatment of IMN has been delineated in the KDIGO guideline, from the perspective of evidence-based medicine. Severe clinical manifestations of IMN should prompt initial treatment with corticosteroids and alkylating agents and (or) calcineurin inhibitors (CNI) ,in a monthly altering manner. Patients with 24-hour urinary protein of <4 g and absence of nephrotic syndrome may be treated with conservative therapy. This might be achieved by means of reducing proteinuria, protecting renal function,minimizing complications and improving quality of life.关键词
膜性肾病,特发性/KDIGO指南/肾病综合征/糖皮质激素/烷化剂/神经钙调素抑制剂Key words
idiopathic membranous nephropathy/KDIGO guideline/nephritic syndrome/glucocorticosteroid/alkylating agent/ calcineurin inhibitor分类
医药卫生引用本文复制引用
邢昌赢..KDIGO指南解读:特发性膜性肾病治疗[J].中国实用内科杂志,2012,32(12):928-931,4.
