摘要
Abstract
Infectious bovine rhinotracheitis (IBR) is a highly contagious, infectious disease that is caused by bovine herpes-virus-1(BHV-1). In addition to causing respiratory disease, this virus can cause conjunctivitis, abortions, encephalitis, and generalized systemic infections. IBR was originally recognized during the early 1950's in Colorado feedlots. There is no direct treatment for the infection and the best way to control IBR is to vaccinate before a disease outbreak occurs. Nowadays, conventional IBR vaccines have been, and still are, routinely used in many countries, the glycoprotein E (gE)-deleted vaccines, either as a live or as a inactivated vaccine, have been commercialized in the European Union. In this review, we discussed the progress in development of gene-deleted vaccine, subunit vaccine, viral vector vaccine and DNA vaccine.关键词
牛传染性鼻气管炎/基因缺失疫苗/亚单位疫苗/活载体疫苗/DNA疫苗Key words
infectious bovine rhinotracheitis/ gene-deleted vaccine/ subunit vaccine/ viral vector vaccine/ DNA vaccine分类
农业科技
