中国畜牧兽医2012，Vol.39Issue(12)：82-88,7.
谷氨酰胺替代饲用抗生素对黄羽肉鸡免疫器官指数及小肠黏膜免疫的影响
The Effects of Glutamine Substitution for Antibiotics Feed Additive on Immune Organ Indexes and Intestinal Mucosal Immune of Yellow Broilers
摘要
Abstract
The experiment was conducted to study the effects of glutamine replacing antibiotics in diet on immune organ indexes and intestinal mucosal immune function of the Yellow broilers. One hundred eighty Yellow broilers with similar weight and good health for one day old were randomized into two control groups and three trial groups with 3 replicates per group and 12 chickens per replicate. The positive control group was fed with diet supplemented with 0. 3 g/kg nosiheptide and 0. 25 g/kg colistin sulfate premix,negative control group was fed with basal diet,the trial Ⅰ , Ⅱ and Ⅲ groups were fed with diet supplemented with 1,2,3 g/kg glutamine, respectively. The results showed that compared with the positive and negative control groups,the immune organ weight and indexes of trail Ⅰ ,Ⅱ and Ⅲ groups were all no significant difference, respectively,and the difference among the experimental groups were also not significant(P>0. 05). On 45 d lysozyme content in the duodenum, jejunum mucosa protein of broilers in treatment Ⅰ and Ⅱ groups decreased compared with the positive control group(P> 0. 05). The bacteria content of trial Ⅰ ,Ⅱ and Ⅲ groups and the negative control group in duodenal were higher than the positive control group(P<0. 05). On 77 d lysozyme content in duodenum,jejunum,ileum mucosa protein of treatment Ⅰ , Ⅱ and Ⅲ groups had no differences compared with the positive control group(P>0. 05). The SIgA content in duodenum was lower than the negative and the positive control groups. Acetic acid,propionic acid,and total acid concentrations content of the treatment groups in ileum were lower than the positive control group and higher than the negative control group. Therefore, glutamine substitution for antibiotics feed additive seemed to improve cellular immunity and mucosal immunity in intestine of Yellow broilers.关键词
谷氨酰胺/饲用抗生素/黄羽肉鸡/免疫器官指数/肠黏膜免疫Key words
glutamine/feed antibiotic/ Yellow broilers/immune organ index/intestinal mucosal immune分类
农业科技引用本文复制引用
李虎,李海英,李晓斌,翟卫爽,杨开伦..谷氨酰胺替代饲用抗生素对黄羽肉鸡免疫器官指数及小肠黏膜免疫的影响[J].中国畜牧兽医,2012,39(12):82-88,7.基金项目
新疆维吾尔自治区高新技术研究发展计划项目(200911113). （200911113）
