中国畜牧兽医2012，Vol.39Issue(12)：144-149,6.
精原干细胞介导法制备转基因羊的研究进展
Research Progress on Transgenic Sheep Produced by Spermatogonial Stem Cell-Mediated
摘要
Abstract
Spermatogonial stem cell-mediated is to transfer the exogenous genes into the animal spermatogonia and the exogenous genes was integrated into its genome. With the original spermatogonial stem cells (SSCs) differentiation into sperm, the exogenous genes were expressed in their own offspring through fertilization. In recent years, people have realized its huge applications prospect and advantages in producing transgenic animals with the deepen research of SSCs. Then, the biological characteristics of SSCs as well as the principle of carrying exogenous gene into animal genome was described to clarify its theoretical mechanisms in preparation of transgenic animals, meanwhile, the research status of spermatogonial stem cell-mediated was introduced, especially for its application in the transgenic goat or sheep production.关键词
精原干细胞介导法/外源基因/转基因羊Key words
spermatogonial stem cell-mediated/exogenous gene/transgenic sheep分类
农业科技引用本文复制引用
邱峰龙,李碧春..精原干细胞介导法制备转基因羊的研究进展[J].中国畜牧兽医,2012,39(12):144-149,6.基金项目
转基因生物新品种培育重大专项(2011ZX08008-003) （2011ZX08008-003）
国家高技术研究发展计划(2011AA100307-04) （2011AA100307-04）
江苏高校优势学科建设工程资助项目. （）
