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我国儿童用药风险因素的文献统计分析

李辉 张锦文 阳波 龚时薇

中国药房2012,Vol.23Issue(37):3466-3469,4.
中国药房2012,Vol.23Issue(37):3466-3469,4.DOI:10.6039/j.issn.1001-0408.2012.37.04

我国儿童用药风险因素的文献统计分析

Literature Statistical Analysis of Risk Factors of Pediatric Medication in China

李辉 1张锦文 1阳波 2龚时薇3

作者信息

  • 1. 华中科技大学同济医学院附属同济医院药学部,武汉430030
  • 2. 南华大学附属第一医院药剂科,湖南衡阳421001
  • 3. 华中科技大学同济医学院药学院,武汉430030
  • 折叠

摘要

Abstract

OBJECTIVE: To explore some effective management measures for rational use of pediatric medication in China. METHODS: 1 298 literatures about pediatric medication in the hospitals were collected from 1999 to 2010. The main risk types and risk factors of pediatric medication were analyzed from macroscopic and microcosmic perspective. RESULTS: 4 objective factors and 2 subjective factors contributed to forming the risks of pediatric medication. The objective factors were made up of pediatric medication policies, medical technology, educational level for patient guardian, pediatric physical character; and the subjective factors included moral hazard and behavioral risk. There were 5 key risks of pediatric medication existed in the practice, including incorrect medicine combination; inappropriate usage, dosage and unsuitable selection of dosage form; the high rate of antibiotics use; inadequate explanation of usage, and dosage safety information in pediatric drug package inserts; and wide clinical use of high risk drugs for children, such as Cephalosporin antibiotics, and TCM injection. CONCLUSIONS: It is necessary to set up the national incentive policy of pediatric medicine R&D and monitoring mechanism of rational drug use. In the hospital, great importance should be attached to construct the special management system of pediatric medicine, and improve drug use monitoring and the professional knowledge of patients guardian.

关键词

儿童用药/风险因素/文献/统计分析/管理措施

Key words

Pediatric medication/ Risk factor/ Literature/ Statistical analysis/ Management strategy

分类

医药卫生

引用本文复制引用

李辉,张锦文,阳波,龚时薇..我国儿童用药风险因素的文献统计分析[J].中国药房,2012,23(37):3466-3469,4.

基金项目

国家自然科学基金青年基金项目(70903025) (70903025)

中国药房

OACSCDCSTPCD

1001-0408

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