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我院2008-2010年细菌耐药监测及抗菌药物应用分析

王霞 王晨

中国药房2012,Vol.23Issue(38):3590-3593,4.
中国药房2012,Vol.23Issue(38):3590-3593,4.DOI:10.6039/j.issn.1001-0408.2012.38.13

我院2008-2010年细菌耐药监测及抗菌药物应用分析

Surveillance of Bacterial Resistance and Analysis of the Utilization of Antibiotics in Our Hospital from 2008 to 2010

王霞 1王晨2

作者信息

  • 1. 首都医科大学附属北京佑安医院药学中心,北京100069
  • 2. 首都医科大学附属北京佑安医院临床检验中心,北京100069
  • 折叠

摘要

Abstract

OBJECTIVE: To investigate the distribution of pathogen, change of bacterial resistance and the utilization of antibiotics in our hospital from 2008 to 2010, and to provide reference for rational use of antibiotics in the clinic. METHODS: DDDs of antibiotics and bacterial resistance of inpatient of our hospital from 2008 to 2010 were analyzed retrospectively. RESULTS: 3 185 strains of pathogens were isolated in 3 years, among which Gram-negative bacteria, Gram-positive bacteria and fungal strains accounted for 55.63%, 27.40% and 16.95%. The detection rate of Gram-positive and Gram-negative bacteria showed ascendant trend year after year. The general bacteria were Escherichia coli, Coagulase negative Staphylococcus, enterococcus, Klebsiella pneumoni ae and Pseudomonsa aeruginosa. The first 3 antibiotics in the list of DDDs were cephalosporins, quinolones and cephalomycin. CONCLUSION: We should strictly implement the Guiding Principles for Clinical Application of Antibacterials, strengthen surveillance of bacterial resistance and select drugs according to the types of pathogenic bacteria and results of drug susceptibility.

关键词

抗菌药物/用药频度/耐药分析

Key words

Antibacterial/ DDDs/ Analysis of drug resistance

分类

医药卫生

引用本文复制引用

王霞,王晨..我院2008-2010年细菌耐药监测及抗菌药物应用分析[J].中国药房,2012,23(38):3590-3593,4.

中国药房

OACSCDCSTPCD

1001-0408

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