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牛蒡子化学成分的分离与鉴定

李卓恒 于彩平 管海燕 卢来春

中国药房2012,Vol.23Issue(39):3696-3699,4.
中国药房2012,Vol.23Issue(39):3696-3699,4.DOI:10.6039/j.issn.1001-0408.2012.39.17

牛蒡子化学成分的分离与鉴定

Separation and Identification of Chemical Constituents of Arctium lappa

李卓恒 1于彩平 1管海燕 1卢来春1

作者信息

  • 1. 第三军医大学大坪医院/野战外科研究所药学部,重庆400042
  • 折叠

摘要

Abstract

OBJECTIVE: To separate and identify chemical constituents in the seeds of Arctium lappa. METHODS: Compounds were isolated with silica gel and Sephadex LH-20 gel column chromatography, and its structures were identified on the basis of physiochemical property and spectral analysis. RESULTS: 10 compounds were isolated and identified as β-sitosterol (1), arc tigenin (2), matairesinol (3), lappaol B (4), lappaol A (5), lappaol F (6), arctiin (7), 8-hydroxypinoresinol (8), ( + )-Frax iresinol (9) and daucosterol (10). Compound 8, 9 were obtained form the seeds of A. Lappa for the first time. CONCLUSION: The study provides reference for further study of A. Lappa.

关键词

牛蒡子/化学成分/分离/结构鉴定

Key words

Arctium lappa/ Chemical constituents/ Separation/ Structure identification

分类

医药卫生

引用本文复制引用

李卓恒,于彩平,管海燕,卢来春..牛蒡子化学成分的分离与鉴定[J].中国药房,2012,23(39):3696-3699,4.

基金项目

国家自然科学基金资助项目(30973908) (30973908)

重庆市科技攻关计划项目(CSTC,2009AC5025) (CSTC,2009AC5025)

重庆市科技型中小企业技术创新项目(11C26215113529) (11C26215113529)

中国药房

OACSCDCSTPCD

1001-0408

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