中国药房2012,Vol.23Issue(39):3696-3699,4.DOI:10.6039/j.issn.1001-0408.2012.39.17
牛蒡子化学成分的分离与鉴定
Separation and Identification of Chemical Constituents of Arctium lappa
摘要
Abstract
OBJECTIVE: To separate and identify chemical constituents in the seeds of Arctium lappa. METHODS: Compounds were isolated with silica gel and Sephadex LH-20 gel column chromatography, and its structures were identified on the basis of physiochemical property and spectral analysis. RESULTS: 10 compounds were isolated and identified as β-sitosterol (1), arc tigenin (2), matairesinol (3), lappaol B (4), lappaol A (5), lappaol F (6), arctiin (7), 8-hydroxypinoresinol (8), ( + )-Frax iresinol (9) and daucosterol (10). Compound 8, 9 were obtained form the seeds of A. Lappa for the first time. CONCLUSION: The study provides reference for further study of A. Lappa.关键词
牛蒡子/化学成分/分离/结构鉴定Key words
Arctium lappa/ Chemical constituents/ Separation/ Structure identification分类
医药卫生引用本文复制引用
李卓恒,于彩平,管海燕,卢来春..牛蒡子化学成分的分离与鉴定[J].中国药房,2012,23(39):3696-3699,4.基金项目
国家自然科学基金资助项目(30973908) (30973908)
重庆市科技攻关计划项目(CSTC,2009AC5025) (CSTC,2009AC5025)
重庆市科技型中小企业技术创新项目(11C26215113529) (11C26215113529)