摘要
Abstract
OBJECTIVE: To observe the clinical efficacy of tramadol for patient controlled intravenous analgesia after different orthopedic surgeries. METHODS: 192 ASA physical status Ⅰ ～Ⅱ patients, scheduled for elective orthopedic surgery, were divided into 6 groups according to operative site: upper extremity long bone surgery group (group I ) , shoulder and elbow surgery group (group Ⅱ ), lower limb long bone surgery group (group Ⅲ), ankle surgery group (group Ⅳ), hip and knee surgery group (group V ), spinal and pelvic group (group ⅥVI). 10 min before the end of surgery, anesthesia pump was opened and connected to patients for patient controlled intravenous analgesia, and the formula of analgesic solution was as follows: tramadol 15 mg·kg-1 combined with granisetron 9 mg were used to antiemetics. The vital signs were recorded when being conscious and 2,4,12,24 and 48 h after operation, and pain score (visual analogue scale, VAS) and sedation score (Ramsay score) were conducted. The incidence of adverse drug reaction and degree of satisfaction were observed. RESULTS: There was no statistical significance in related vital signs in different groups at different time points (P>0.05); there was no statistical significance in Ramsay score in different groups at different time points (P>0.05); VAS scores of each group 2 and 4 h after operation were between 3～6 points and significantly higher than other time points, there was statistical significance (P<0.05); the VAS scores of group Ⅱ and Ⅳ 2,4,12 and 24 h after operation were between 3～6 points and higher than 1～3 of other groups at the same time interval. There was statistical significance (P<0.05). There was no statistical significance in the incidence of ADR (P>0.05). No serious ADR was found in each group. The degrees of satisfaction in group I and IV were significantly lower than in other groups, there was statistical significance (P<0.05). CONCLUSION: Tramadol 15 mg·kg-1 is effective for patient controlled intravenous analgesia after most orthopedic surgeries without obvious ADR, but it is a bit week for analgesia of shoulder and elbow surgery and ankle surgery.关键词
骨伤手术/曲马多/患者自控静脉镇痛/效果Key words
Orthopedic surgery/ Tramadol/ Patient controlled intravenous analgesia/ Effect分类
医药卫生
