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桃红四物汤预防胫骨骨折髓内钉内固定术后下肢深静脉血栓发生的临床观察

孙毅 程慎令

中国药房2012,Vol.23Issue(43):4103-4105,3.
中国药房2012,Vol.23Issue(43):4103-4105,3.DOI:10.6039/j.issn.1001-0408.2012.43.28

桃红四物汤预防胫骨骨折髓内钉内固定术后下肢深静脉血栓发生的临床观察

Efficacy Observation of Taohong Siwu Tang for the Prevention of Deep Vein Thrombosis after Intramedullary Nailing Fixation of Tibial Fractures

孙毅 1程慎令1

作者信息

  • 1. 滕州市中心人民医院,山东滕州277500
  • 折叠

摘要

Abstract

OBJECTIVE: To observe the clinical efficacy of Taohong siwu tang to prevent formation of deep vein thrombosis (DVT) in patients with tibial fractures after intramedullary nailing fixation. METHODS: 89 patients were randomly divided into treatment group (43 patients,Taohong siwu tang 150 mL,po,twice a day, consecutive 7 days) and control group (46 patients,hypodermic injection of low molecular weight heparin 4 000 U once a day, consecutive 7 days). 1 week later, vein thrombosis of lower extremities was detected by B ultrasound, the incidence of DVT, plasma level of ET and DDC were observed and determined. RESULTS: The incidence of DVT had no significant difference between 2 groups (P>0.05) and average daily cost of anticoagulation in treatment group was significantly lower than control group(P<0.05). The plasma levels of ET in 2 groups 14 days after operation was significantly lower than 3 days after operation (P< 0.05), and the plasma level of ET in treatment group was significactly lower than control group(P<0.05).CONCLUSION: Taohong siwu tang can effectively prevent the occurrence of DVT after intramedullary nailing fixation of tibial fracture and cost less.

关键词

桃红四物汤/胫骨骨折/髓内钉/下肢深静脉血栓

Key words

Taohong siwu tang/ Tibial fractures/ Intramedullary nailing/ Deep vein thrombosis of lower extremities

分类

医药卫生

引用本文复制引用

孙毅,程慎令..桃红四物汤预防胫骨骨折髓内钉内固定术后下肢深静脉血栓发生的临床观察[J].中国药房,2012,23(43):4103-4105,3.

中国药房

OACSCDCSTPCD

1001-0408

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