摘要
Abstract
OBJECTIVE: To observe the clinical efficacy of small doses of midazolam and small doses of midazolam combined with fentanyl for anxiety, stress and visceral traction reaction of delivery woman undergoing cesarean section. METHODS: 100 ASA I delivery women aged 22~35 years old were divided into group A and B according to the situation of drug use. Group A and B received given intravenous bolus injection of 0.03 nig-kg-1 midazolam before skin incision, and group B was additionally given intravenous bolus injection of 0.75 ng-kg-1 fentanyl after 2 minutes. RESULTS: After treatment, there were significant anxio-lytic effects in both 2 groups. Specifically, there was no significant change in group A about BP, HR, SpO2 and RR, while those were decreased in group B, compared with group A at the same time point (P<0.05). There were similar in traction reaction, sedation, forgetting rate 24 h after surgery in 2 groups(P>0.05). There was no significant ADR found. CONCLUSION: Small doses of midazolam and small doses of midazolam combined with fentanyl for cesarean section can both get satisfactory results in sedative, anxiolytic, postoperative forgotten and anti-visceral response. However, only small dose midazolam will have less effect on breathing and circulation and can get better results in cesarean section.关键词
咪达唑仑/芬太尼/剖宫产术Key words
Midazolam/Fentanyl/Cesarean section分类
医药卫生
