中国药业2012,Vol.21Issue(21):11-12,2.
435株铜绿假单胞菌的临床分布与耐药性分析
Analysis on Clinical Distribution and Drug Resistance in 435 Strains of Pseudomonas Aeruginosa
孙鑫晔 1王栋 1袁耀辉 1王丽华1
作者信息
- 1. 河北省邢台市第三医院,河北 邢台 054000
- 折叠
摘要
Abstract
Objective To investigate the clinical distribution and drug resistance of Pseudomonas aeruginosa(PAE) in hospitals, and to provide the evidence for rational use of antibacterial drugs in clinic. Methods The drug sensitivity test on PAE isolated from various samples collected in our hospital from January to December 2011 was carried out by use of K - B method. Then the results were performed the statistical analysis. Results Four hundred thirty - five strains of PAE were isolated. Of which, 370 strains were isolated from sputum samples, accounting for 85. 06% . The high incidence inpatients areas were the departments of neurosurgery, ICU and respiration. The resistance to ceftazime was lowest(15. 64% ), the resistances to cefepime, amikacin, aztreonam, meropenem, cefoperazone and sulbactam were relatively lower, which were 36. 25% , 36. 96% , 45. 54% , 47. 89% and 48.94% respectively. Conclusion The PAE's drug resistance rate in our hospital is on a high position. Therefore, the drug - resistance surveillance and monitoring must be enhanced to provide the updated information for clinical medication. Doctors should choose antibacterial drugs reasonably to reduce the generation of drug - resistant bacterial strain.关键词
铜绿假单胞菌/耐药性/抗菌药物Key words
Pseudomonas aeruginosa/ drug resistance/ antibacterial drug分类
医药卫生引用本文复制引用
孙鑫晔,王栋,袁耀辉,王丽华..435株铜绿假单胞菌的临床分布与耐药性分析[J].中国药业,2012,21(21):11-12,2.