中国药业2012，Vol.21Issue(23)：8-9,2.
高效液相色谱法与化学发光酶免疫分析法测定丙戊酸血药浓度的比较
Comparison of HPLC and CLEIA for Determining the Serum Valproic Acid Concentrations
范毅 1钱南萍 1陈斌1
作者信息
- 1. 江苏省泰州市人民医院,江苏泰州 225300
- 折叠
摘要
Abstract
Objective To compare the results from the determination of the serum valproic acid concentrations by HPLC and CLEIA. Methods Using HPLC and CLEIA to determine the serum concentrations of valproic acid was used in treatment of 46 cases before using medicine,then compared the relativity of the two methods. Results Linear regression examination is used for the two methods,the linear regression function was Y = 0. 980 2 X + 2. 477 7 ( r = 0. 979 3). There were no significant statistical differences between the results determined by two methods ( P > 0. 05). Conclusion There is good relativity between the serum valproic acid concentrations by HPLC and CLEIA. The determination results didn t need mutual correction. Both methods can be used for routine determination of the serum valproic acid concentrations.关键词
丙戊酸/高效液相色谱法/化学发光酶免疫法/血药浓度Key words
valproic acid/HPLC/CLEIA/serum concentration分类
医药卫生引用本文复制引用
范毅,钱南萍,陈斌..高效液相色谱法与化学发光酶免疫分析法测定丙戊酸血药浓度的比较[J].中国药业,2012,21(23):8-9,2.
