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Is cerebral cavernous malformation a pre-glioma lesion?

ZHANG Ji-yang MING Zong-yi WU An-hua

中华医学杂志（英文版）2012，Vol.125Issue(24)：4511-4513,3.

中华医学杂志（英文版）2012，Vol.125Issue(24)：4511-4513,3.DOI:10.3760/cma.j.issn.0366-6999.2012.24.033

Is cerebral cavernous malformation a pre-glioma lesion?

ZHANG Ji-yang ¹MING Zong-yi ²WU An-hua³

作者信息

1. Department of Neurosurgery, First Affiliated Hospital of China Medical University, Shenyang, Liaoning 110001, China
2. Department of Neurosurgery, 463 Hospital, Shenyang, Liaoning 110042, China
3. Department of Neurosurgery, First Affiliated Hospital of China Medical University, Shenyang, Liaoning 110001, China
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摘要

Abstract

Glioma is the most malignant tumor in the brain,the origin of glioma is still unknown.Recently some papers indicated that glioma may be developed from cerebral cavernous malformation (CCM).We describe a man with a right temporal lobe CCM,after gamma-knife radiotherapy,the patient developed a low-grade astrocytoma in the area of the preexistent CCM.This case,together with other reports,may indicated an oncogenetic properties of CCM,and we proposed that CCM may be a pre-glioma lesion.

关键词

glioma/ cerebral cavernous malformation/ radiotherapy

Key words

glioma/ cerebral cavernous malformation/ radiotherapy

引用本文复制引用

ZHANG Ji-yang,MING Zong-yi,WU An-hua..Is cerebral cavernous malformation a pre-glioma lesion?[J].中华医学杂志（英文版）,2012,125(24):4511-4513,3.

基金项目

This work was supported by grants from National Natural Science Foundation of China (No.81172409),and National "863" Key Project (No.2012AA02A508). （No.81172409）

中华医学杂志（英文版）

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ISSN：0366-6999

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