中国中西医结合杂志2012，Vol.32Issue(12)：1602-1606,5.
双参通冠胶囊治疗急性心肌梗死直接PCI术后患者的临床观察
Clinical Efficacy Evaluation of Shuangshen Tongguan Capsule on Acute Myocardial Infarction Patients after Direct Percutaneous Coronary Intervention
摘要
Abstract
Objective To evaluate the therapeutic efficacy of Shuangshen Tongguan Capsule (STC) on acute myocardial infarction (AMI) patients after direct percutaneous coronary intervention (PCI). Methods U-sing a randomized controlled method, AMI patients with elevated ST segment after successful direct PCI were randomly assigned to the control group (62 cases) and the treatment group (67 cases). On the basis of the standard Western medical treatment, patients in the treatment group took STC, while those in the control group took STC placebos, 4 pills each time, three times daily. The Chinese medicine syndrome integrals, the cardiac function in the resting and loading states, the microcirculation perfusion rate, and the changes of Seattle Angina Scale score were evaluated after 6 months of treatment. Results Five cases were lost, accounting for 3. 88%. Six months later the Chinese medicine syndrome integrals obviously decreased, the efficacy of Chinese medicine syndrome was enhanced, the LVEF in the loading state and the percentage of normal myocardium obviously increased, anterior myocardial infarction segments with increased k value of the microcirculation perfusion increased, the total score of Seattle Angina score, the satisfactory degree of the treatment, and the integrals for the disease recognition degree were significantly enhanced (all P＜0. 05). Conclusions STC could improve the angina symptoms of AMI patients after direct PCI and elevate their heart functions. It has certain roles in improving microcirculation perfusion of myocardium, thus elevating patients' quality of life.关键词
双参通冠方/血管新生/急性心肌梗死/经皮冠状动脉介入Key words
Shuangshen Tongguan Capsule/ angiogenesis/ acute myocardial infarction/ percutaneous coronary intervention引用本文复制引用
王永刚,齐婧,郑刚,罗文平,于远望,尤金枝..双参通冠胶囊治疗急性心肌梗死直接PCI术后患者的临床观察[J].中国中西医结合杂志,2012,32(12):1602-1606,5.基金项目
国家自然科学基金资助课题(No.30973830,30901895) （No.30973830,30901895）
陕西省中医药管理局中医药科研专项资金项目(No.lc45) （No.lc45）
国家中医药管理局重点专科心血管病科建设项目(国中医药政发[2012]2号) （国中医药政发[2012]2号）
陕西省第五批重点专科心脑血管病科建设项目(陕财办社[2009]153号) （陕财办社[2009]153号）
