中国中西医结合杂志2012，Vol.32Issue(12)：1624-1627,4.
针刺对慢性坐骨神经痛患者治疗后静息态脑默认网络影像的影响
Effects of Acupuncture on Default Mode Network Images of Chronic Sciatica Patients in the Resting Network State
摘要
Abstract
Objective To observe the functional magnetic resonance imaging (fMRI) data changes of default mode network (DMN) in chronic sciatica patients in the resting network state treated by acupuncture, and to study the correlation between DMN and the consisting effects after acupuncture analgesia. Methods Weizhong (BL40) and Huantiao (GB30) of the patients' lower limbs were selected as the main points to acupuncture for ten times. The whole brain was scanned using fMRI. The independent component analysis (ICA) was adopted to get DMN information. The brain DMN function link was analyzed in the two groups of subjects. Results The DMN images were obtained in all subjects after DMN fMRI data processing. The main DMN differences between the sciatica patients group and the healthy control group were demonstrated as decreased activities of DLPFC and anterior cingulate cortex (ACC). After acupuncture, activities of these regions basically recovered to normal. The DMN of healthy volunteers shown by fMRI data in the RNS mainly existed in the precunes, BA7, BA10, and ACC. Conclusion MRI images of DMN in the RNS could reflect chronic pain, which was suitable for studies on the effects after acupuncture analgesia.关键词
针刺镇痛/慢性坐骨神经痛/静息状态功能性磁共振/脑默认网络Key words
acupuncture analgesia/ chronic sciatica/ functional magnetic resonance imaging in the resting network state/ default mode network引用本文复制引用
李霁,董竞成,乐晶晶,汤伟军..针刺对慢性坐骨神经痛患者治疗后静息态脑默认网络影像的影响[J].中国中西医结合杂志,2012,32(12):1624-1627,4.基金项目
上海市卫生局科研基金资助项目(No.2009013) （No.2009013）
