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鸭脚木指纹图谱研究及3种三萜皂苷类化合物的含量测定

吴春 王国才 段营辉 吴霞 周光雄 叶文才 李药兰

中药材2012,Vol.35Issue(7):1062-1065,4.
中药材2012,Vol.35Issue(7):1062-1065,4.

鸭脚木指纹图谱研究及3种三萜皂苷类化合物的含量测定

Study on the HPLC Fingerprint and Simultaneous Determination of Three Triterpene Glycosides in Schefflera heptaphylla

吴春 1王国才 1段营辉 1吴霞 1周光雄 1叶文才 1李药兰1

作者信息

  • 1. 暨南大学中药及天然药物研究所/中药药效物质基础及创新药物研究广东省重点实验室,广东广州510632
  • 折叠

摘要

Abstract

Objective:To establish the HPLC fingerprint and simultaneously determination three triterpene glycosides in Schefflera heptaphylla. Methods:The separation was carried out on an Agilent Zorbax SB-C18(4. 6 mm × 250 mm ,5μm)column eluted with meth-anol-0. 1% glacial acetic acid as the mobile phase,and samples were detected by an evaporative light scattering detector (ELSD). The similarity evaluation system for chromatographic fingerprint of traditional Chinese medicine (Version 2004 A) was used in data analysis. Results: Schefflera heptaphylla from different regions were similar and the separation of three triterpene glycosides was good. Conclusion: This method is simple and reliable. The HPLC fingerprint and contents of three kinds of triterpene glycosides of Schefflera heptaphylla can be used for their quality control.

关键词

鸭脚木/HPLC-ELSD/指纹图谱/三萜皂苷

Key words

Schefflera heptaphylla (L ) Frodin/ HPLC-ELSD/ Fingerprint/ Triterpene glycosides

分类

医药卫生

引用本文复制引用

吴春,王国才,段营辉,吴霞,周光雄,叶文才,李药兰..鸭脚木指纹图谱研究及3种三萜皂苷类化合物的含量测定[J].中药材,2012,35(7):1062-1065,4.

基金项目

广东省自然科学基金团队项目(8351063201000003) (8351063201000003)

中药材

OA北大核心CSCDCSTPCDMEDLINE

1001-4454

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