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昆明山海棠根皮化学成分研究

谢富贵 李创军 杨敬芝 罗永明 张东明

中药材2012,Vol.35Issue(7):1083-1087,5.
中药材2012,Vol.35Issue(7):1083-1087,5.

昆明山海棠根皮化学成分研究

Study on Chemical Constituents from the Root Bark of Tripterygium hypoglaucum

谢富贵 1李创军 2杨敬芝 1罗永明 1张东明2

作者信息

  • 1. 中国医学科学院北京协和医学院药物研究所/天然药物活性物质与功能国家重点实验室,北京100050
  • 2. 江西中医学院,江西南昌330004
  • 折叠

摘要

Abstract

Objective: To study the chemical constituents of the root bark of Tripterygium hypoglaucum. Methods: Column chroma-tography was used to separate the chemical constituents. The structures were determined by application of spectroscopic (NMR,MS) and chemical methods. Results: Eleven compounds were isolated and identified as 4'-O-( - ) methylepigallocatechin ( 1 ) , 3,4-dim-ethoxyphenyl-β-D-glucopyranoside (2) ,3 ,4,5-trimethoxyphenyl-β-D-glucopyranoside (3) , (2R,3R)-3 ,5 ,7 ,3' ,5'-pentahydroxyflavan (4) ,2-O-deacetyleuonine (5) ,tripfordine C (6) ,peritassine A (7) ,hypoglaunine C (8) ,wilfortrine (9) ,wilforgine (10) and wilfor-dine (11). Conclusion: Compounds 1 ~ 6 are isolated from this plant for the first time.

关键词

昆明山海棠/化学成分/生物碱

Key words

Tripterygium hypoglaucum ( Level. ) Hutch/ Chemical constituents/ Alkaloids

分类

医药卫生

引用本文复制引用

谢富贵,李创军,杨敬芝,罗永明,张东明..昆明山海棠根皮化学成分研究[J].中药材,2012,35(7):1083-1087,5.

基金项目

国家科技支撑计划(2009BA173B03 ()

2011BAI01B05) ()

中药材

OA北大核心CSCDCSTPCD

1001-4454

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