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蒲黄炒炭前后化学组分的变化及谱效相关性研究

陈佩东 孔祥鹏 李芳 丁安伟

中药材2012,Vol.35Issue(8):1221-1224,4.
中药材2012,Vol.35Issue(8):1221-1224,4.

蒲黄炒炭前后化学组分的变化及谱效相关性研究

Spectrum-active Relation Research on Typha angustifolia before and after Carbonized

陈佩东 1孔祥鹏 1李芳 1丁安伟1

作者信息

  • 1. 南京中医药大学药学院,江苏南京210046
  • 折叠

摘要

Abstract

Objective: To study the components of Typha angustifolia change before and after carbonized and the correlation with its effective. Methods: The chemical constitutions between the pollen and its carbonized product were compared by UPLC-MASS and their thrombin activity was tested. Results: The change of components was significant especially the flavonoids. The content of fla-vonoid glycoside was reduced obviously and the thrombin activity showed the main difference was quercetin and isorhamnetin. Conclusion; The flavonoids in pollen typha may be the main factors in their thrombin activity.

关键词

蒲黄/蒲黄炭/黄酮/凝血

Key words

Typha angustifolia L. /Carbonized Typha angustifolia L. /Flavonoids/ Thrombin

分类

医药卫生

引用本文复制引用

陈佩东,孔祥鹏,李芳,丁安伟..蒲黄炒炭前后化学组分的变化及谱效相关性研究[J].中药材,2012,35(8):1221-1224,4.

基金项目

国家行业专项(20110700707) (20110700707)

中药材

OA北大核心CSCDCSTPCDMEDLINE

1001-4454

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