中药材2012，Vol.35Issue(8)：1230-1233,4.
西南产玄参药材的HPLC指纹图谱研究
HPLC Fingerprint of Scrophulariae Radix from Southwest China
周雯 1蒋林 1王晓娟 1陶红 1郑锡康 1胡继藤1
作者信息
- 1. 中山大学药学院生药与天然药物化学实验室,广东广州510006
- 折叠
摘要
Abstract
Objective: To establish HPLC fingerprints of Scrophulariae Radix methanol extract from both the different southwest origin and market,provide evidence for its quality control. Methods; 11 batches of samples analysis was performed on C18 column with gradient mobile phase of acetonitrile-0. 4% acetic acid, the monitoring wavelength was at 260 nm with the flow rate of 1. 0 mL/min, detective course was finished in 55 min. Results: Established the HPLC fingerprint common patterns by using harpagoside and cinnam-ic acid as the index components, and similarity with different origin rude drugs and pieces was compared. The similarity was above 0. 901. Conclusion; This method contributes to the fast comprehensive evaluation of material quality and can be used specifically for standardized planting and quality control of Scrophulariae Radix.
关键词
玄参/哈巴俄苷/肉桂酸/高效液相色谱法/指纹图谱Key words
Scrophulariae Radix/ Harpagoside/ Cinnamic acid/ HPLC/ Fingerprint分类
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周雯,蒋林,王晓娟,陶红,郑锡康,胡继藤..西南产玄参药材的HPLC指纹图谱研究[J].中药材,2012,35(8):1230-1233,4.
