组织工程与重建外科杂志2012，Vol.8Issue(5)：264-266,3.DOI:10.3969/j.issn.1673-0364.2012.05.005
ANGPTL-1基因在老化鼠尾皮肤成纤维细胞中的表达及意义
The Expression and Meaning of ANGPTL1 Gene in Skin Fibroblast of Aging Mouse Tail
宋仁刚1
作者信息
- 1. 518020 广东省深圳市 深圳市人民医院整形外科
- 折叠
摘要
Abstract
Objective To explore the expression of ANGPTL-1 gene, collagen and hyaluronic acid (HA) in skin fibroblast of aging mouse tail in vitro. Methods Primary mouse skin fibroblasts were collected in young and old mouse group. RT-PCR was used to measure expression of collagen and hyaluronic acid. Results RT-PCR assay showed that the express of ANGPTL1 is higher in young group than in older group. There was significant difference between 2 groups (P<0.01). Conclusion ANGPTL-1 may be used as an effective factor to delay skin aging.关键词
血管生成素样蛋白/老化/皮肤成纤维细胞/胶原蛋白/透明质酸(HA)Key words
ANGPTL-1/ Aging/ Fibroblast/ Collagen/ Hyaluronic acid (HA)分类
生物科学引用本文复制引用
宋仁刚..ANGPTL-1基因在老化鼠尾皮肤成纤维细胞中的表达及意义[J].组织工程与重建外科杂志,2012,8(5):264-266,3.
