重庆医学2013,Vol.42Issue(5):490-492,3.DOI:10.3969/j.issn.1671-8348.2013.05.004
儿童嗜肺军团菌肺炎合并肺炎支原体感染的临床研究
Clinical research of legionella pneumophila pneumonia combined with mycoplasma pneumoniae infection in children
摘要
Abstract
Objective To summarize the clinical features of legionella pneumophila pneumonia (Lp) combined with mycoplasma pneumoniae (Mp) infection in children,and to accumulate materials for the clinical prevention and treatment. Methods Clinical data of 95 cases infected with legionella pneumophila pneumonia (in which 35 cases combined with Mp infection) in the Ninth People s Hospital of Chongqing from January 2010 to June 2012 were collected,and their clinical features were compared and analyzed. Results Childhood pneumonia due to LP and MP mixed infection was more common in urban preschool children. Compared with the LP pneumonia group,most cases in mixed infection group had performance of high thermal peak and long thermal path. The cases of positive signs of lung,increased heart rate,enlargement of lymph nodes and liver were significantly increased(P<0. 05). And with auxiliary examination,there were performance of large areas of plaques shadow and pleural effusion in Chest X-ray,WBC increase, CRP increase,positive ECG (tachycardia/ST-T changes) ,CK-MB increase and cases with abnormal liver function significantly increased (P<0.05). And the required treatment time was significantly prolonged (P<0. 05). Conclusion Children LP pneumonia combined with MP mixed infection can lead to population disease, which usually performs with serious pulmonary symptoms and signs,and is easily combined with damages of multiple extra-pulmonary organs and systems. It should be researched in large sample and multi-center study,in order to obtain reliable information on the infection status and thus provide ideas and measures for the clinical prevention and treatment.关键词
肺炎,支原体/肺炎/儿童/嗜肺军团菌Key words
pneumonia, mycoplasma/ pneumonia/ children/ legionella pneumophila引用本文复制引用
何志慧,周玉福,石远滨..儿童嗜肺军团菌肺炎合并肺炎支原体感染的临床研究[J].重庆医学,2013,42(5):490-492,3.基金项目
国家自然科学基金资助项目(10971168) (10971168)