重庆医学2013，Vol.42Issue(7)：755-756,2.DOI:10.3969/j.issn.1671-8348.2013.07.014
非体外循环冠状动脉搭桥术围术期脑氧供需及凝血纤溶系统的变化研究
Study on change of cerebral oxygen supply and demand,coagulation and fibrinolysis system of off-pump coronary artery bypass during perioperative period
任明明 1韩振 1冯钢 1许志锋1
作者信息
- 1. 北京大学深圳医院心血管外科,广东深圳,518036
- 折叠
摘要
Abstract
Objective To study the variation regularity of cerebral oxygen supply and demand,coagulation and fibrinolysis sys tem of off pump coronary artery bypass during perioperative period. Methods 24 patients treated with off pump coronary artery bypass in our hospital from October 2009 to January 2012 were selected as the observation group,and 24 patients treated with car diopulmonary bypass coronary artery bypass grafting at the same time were selected as the control group. Then the indexes of cere bral oxygen supply and demand,coagulation and fibrinolysis system before heparinization,immediately after operation and at post operative 1,6 h were compared between the two groups. Results ACT,APTT and Fig before heparinization,immediately after op eration and at postoperative 1,6 h in the observation group were higher than those in the control group,CD62p was lower than that in the control group; SjvO2 and CjvO2 were all higher than those in the control group, while CERO2 and Ca jO2 were all lower than those in the control group,all differences between the two groups showing statistical significance(P-<0. 05). Conclusion The cere bral oxygen supply and demand,coagulation indexes of off pump coronary artery bypass during perioperative period are all better than those of cardiopulmonary bypass coronary artery bypass grafting. In off pump coronary artery bypass, bleeding can be effec tively controlled and the brain injury can be decreased.关键词
冠状动脉分流术/手术期间/氧需求/纤维蛋白溶解/血液凝固/体外循环Key words
coronary artery bypass/operative period/oxygen demand/fibrinolysis/blood coagulation/extracorporeal circulation引用本文复制引用
任明明,韩振,冯钢,许志锋..非体外循环冠状动脉搭桥术围术期脑氧供需及凝血纤溶系统的变化研究[J].重庆医学,2013,42(7):755-756,2.
