|国家科技期刊平台
| 注册
首页|期刊导航|中德临床肿瘤学杂志（英文版）|肝动脉栓塞化疗联合肝复乐治疗晚期肝癌临床疗效观察

肝动脉栓塞化疗联合肝复乐治疗晚期肝癌临床疗效观察

Mingzhi Hao Hailan Lin Qizhong Chen Yubin Hu Dong Zhou Ping Huang YunBin Ye

中德临床肿瘤学杂志（英文版）2013，Vol.12Issue(1)：25-29,5.
✕
中德临床肿瘤学杂志（英文版）2013，Vol.12Issue(1)：25-29,5.DOI:10.1007/s10330-012-1099-1

肝动脉栓塞化疗联合肝复乐治疗晚期肝癌临床疗效观察

Efficacy of transcatheter arterial chemoembolization combined with ganfule on advanced hepatocellular carcinoma

Mingzhi Hao 1Hailan Lin 2Qizhong Chen 1Yubin Hu 2Dong Zhou 1Ping Huang 1YunBin Ye3

作者信息

  • 1. Department of Interventional Radiology, Fujian Provincial Tumor Hospital, Fujian 350014, China
  • 2. Fujian Provincial Key Laboratory of Tumor Translational Medicine, Fujian 350014, China
  • 3. Department of Abdominal Surgery, Fujian Provincial Tumor Hospital, Fujian 350014, China
  • 折叠

摘要

Abstract

Objective: The aim of this study was to evaluate the efficacy of transcatheter arterial chemoembolization (TACE) combined with a Chinese compound preparation of ganfule on advanced hepatocellular carcinoma (HCC). Methods: The study population consisted of 132 advanced HCC patients with Child-pugh A/B. Tumor in all patients was involved with main trunk of portal vein and/or inferior vena cava, or local lymph node metastasis, or distant metastasis. TACE combined with ganfule were performed in 65 patients with advanced HCC (interventional treatment group), 67 patients were treated with traditional Chinese herbal drug alone (Chinese herb group). The prime end point was overall survival (OS), and prognostic factors were analyzed. Results: The median OS was 205 days [95% confidence interval (CI), 155-255 days] in interventional treatment group and 127 days (95% CI, 70-184 days) in Chinese herb group (P < 0.05). The 6-month, 1-year, and 2-year OS rates were 58.9%, 29.1%, 7.7% in interventional treatment group, and 33.3%, 12.3%, 1.8% in Chinese herb group, respectively. The portal vein thrombosis, ECOG performance status (PS) were independent prognostic factors for OS. Conclusion: Ttranscatheter arterial chemoembolization combined with a Chinese compound preparation of ganfule could greatly prolong the OS of advanced HCC patients. The portal vein thrombosis and ECOG PS were independent prognostic factors for OS.

关键词

liver neoplasm/chemoembolization/transcatheter arterial infusion/Chinese herbs/ganfule

Key words

liver neoplasm/chemoembolization/transcatheter arterial infusion/Chinese herbs/ganfule

引用本文复制引用

Mingzhi Hao,Hailan Lin,Qizhong Chen,Yubin Hu,Dong Zhou,Ping Huang,YunBin Ye..肝动脉栓塞化疗联合肝复乐治疗晚期肝癌临床疗效观察[J].中德临床肿瘤学杂志（英文版）,2013,12(1):25-29,5.

基金项目

Supported by a grant from the Research Foundation of Fujian Provincial Health Department (No.2010-7). （No.2010-7）

中德临床肿瘤学杂志（英文版）

OACSTPCD

2095-9621

访问量0
|
下载量0
段落导航相关论文