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基因芯片筛选畜禽热应激差异表达基因的研究进展

刘丽莉 谢红兵 杨永生 许丹宁 李江长 贺建华

动物营养学报2012,Vol.24Issue(12):2287-2294,8.
动物营养学报2012,Vol.24Issue(12):2287-2294,8.DOI:10.3969/j.issn.1006-267x.2012.12.001

基因芯片筛选畜禽热应激差异表达基因的研究进展

Advances in Screening Differentially Expressed Genes Related to Heat Stress of Livestock and Poultry by Using cDNA Microarray

刘丽莉 1谢红兵 2杨永生 1许丹宁 1李江长 1贺建华1

作者信息

  • 1. 湖南农业大学动物科学技术学院,长沙 410128
  • 2. 湖南科技大学生命科学学院,湘潭 411201
  • 折叠

摘要

Abstract

A series of gene level changes in livestock and poultry caused by heat stress directly affect various organs and tissues of normal physiological function. The technology of cDNA microarray has been widely ap-plied in pathogenic, stress and other aspects of the study of gene expression profile in livestock and poultry. The latest research and application advances in screening differentially expressed genes related to heat stress of livestock and poultry by using the cDNA microarray were summarized, including the analysis of the differenti-ally expressed genes related to heat stress on oxidative damage of tissues and organs, performance, and in vitro cultured cells from different livestock and poultry. The application of cDNA microarray could provide some important methods for searching and validating the biological molecular markers closely related to the body damage caused by heat stress, and play an important reference role in the research of nutritional regulation for heat stress-induced injuries in livestock and poultry.

关键词

基因芯片/畜禽/热应激/差异基因

Key words

cDNA microarray/ livestock and poultry/ heat stress/ differential genes

分类

农业科技

引用本文复制引用

刘丽莉,谢红兵,杨永生,许丹宁,李江长,贺建华..基因芯片筛选畜禽热应激差异表达基因的研究进展[J].动物营养学报,2012,24(12):2287-2294,8.

基金项目

湖南省高校科技创新团队支持计划资助 ()

湖南省博士后基金项目(2011RS4006) (2011RS4006)

动物营养学报

OA北大核心CSCDCSTPCD

1006-267X

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