南方医科大学学报2013，Vol.33Issue(1)：40-43,4.DOI:10.3969/j.issn.1673-4254.2013.01.09
相关函数法用于监控脉冲高强度聚焦超声治疗的准确性研究
Accuracy of correlation function method for evaluating pulsed high intensity focused ultrasound
摘要
Abstract
Objective To investigate the accuracy of ultrasound monitoring during pulsed high intensity focused ultrasound (PHIFU) treatment and improve the sensitivity of ultrasound monitoring of tissue necrosis caused by PHIFU treatment. Methods Bovine liver ex vivo was dot-exposed with HIFU at the therapeutic doses of 2000 J (group A) and 1440 J (group B). The two groups were further divided into groups A1 (power 100 W, duty cycle 100%, irradiate 20 s) A2 (power 100 W, duty cycle 50%, irradiate 40 s), A3 (power 100 W, duty cycle 40%, irradiate 50 s), B1 (power 120 W, duty cycle 100%, irradiate 12 s), B2 (power 100 W, duty cycle 50%, irradiate 24 s), and B3 (power 100 W, duty cycle 40%, irradiate 30 s). The gray scale changes in the ultrasonic images after the exposures were observed, and the correlation function of the image was calculated before and after the exposure. The accuracy of evaluations based on the correlation function and gray-scale changes was compared. Results The correct rate of gray scale-based evaluation of tissue necrosis caused by PHIFU was only 51%, while that by correlation function-based evaluation reached 85%. Conclusion Monitoring of tissue necrosis caused by PHIFU treatment can not rely solely on evaluation of gray-scale change of the ultrasound images, and the correlation function-based evaluation can be more accurate and sensitive for that purpose.关键词
脉冲高强度聚焦超声/超声监控/灰度变化/相关函数Key words
pulsed high intensity focused ultrasound/ultrasound monitoring/gray-scale change/correlation function引用本文复制引用
赵欣,邹建中,伍烽,刘芳,焦娇..相关函数法用于监控脉冲高强度聚焦超声治疗的准确性研究[J].南方医科大学学报,2013,33(1):40-43,4.基金项目
国家重点基础研究发展计划(973计划)(2011CB707902) （973计划）
