分析化学2012，Vol.40Issue(10)：1555-1560,6.DOI:10.3724/SP.J.1096.2012.20064
固相萃取-亲水相互作用液相色谱法同时测定环境水样中3种酰胺类化合物
Determination of Three Amide Compounds in Environmental Water by Solid Phase Extraction Coupled with Hydrophilic Interaction Liquid Chromatography
摘要
Abstract
A simple hydrophilic interaction liquid chromatographic ( HILIC) method for the determination of acrylamide (AA), N, N-dimethylformamide (DMF), and N, N-dimethylacetamide (DMAC) in environmental water was developed. A cartridge containing graphitized carbon black was used for solid phase extraction (SPE) of the compounds in environmental water, the sample loaded was 1.0 mL, and then eluted with 1.0 mL acetonitrile, the elution was introduced into the instrument and determined by HPLC coupled with photo-diode array detector (PDA) at 200 nm. A good baseline separation of target compounds was obtained in 11 minutes under the optimum condition of determination. The calibration curves of 3 amides were linear in the concentration range of 0.05- 100 mg/L with correlation coefficients of 0.9999. Overall recoveries were good (84.1% -106%), and the relative standard deviations ranged from 1.8% to 10.4% for the target compounds. The minimum detectable concentrations were 0.01 mg/L. This established method is convenient, sensitive and accurate, and was suitable for the routine detection of trace amide contaminants in environmental water.关键词
亲水相互作用液相色谱/固相萃取/酰胺/环境水样Key words
Hydrophilic interaction liquid chromatography/ Solid phase extraction/ Amide/ Environmental water引用本文复制引用
张明,唐访良,范晓开,徐建芬,陈峰,吴志旭..固相萃取-亲水相互作用液相色谱法同时测定环境水样中3种酰胺类化合物[J].分析化学,2012,40(10):1555-1560,6.基金项目
本文系杭州市环境保护科技项目(No.2011003)资助 （No.2011003）
