高等学校化学学报2013,Vol.34Issue(2):462-466,5.DOI:10.7503/cjcu20120639
磁性蛋白质微胶囊的声化学法构筑
Fabrication of Magnetic Protein Microcapsules by Sonochemical Method
摘要
Abstract
Biocompatible magnetic protein microcapsules ( MPMCs) were prepared by sonochemical method. Under high intensity ultrasonic treatment, the MPMCs were yielded at the interface between the oil liquids containing Fe3O4 nanoparticles and the protein solution within several minutes. Meanwhile, the hydrophobic drugs could be loaded into MPMCs directly via sonochemical method and the activities of proteins and drugs were not destroyed. The sonochemical technique is a very simple and cost-effective method to fabricate MPMCs as drug carriers. Such prepared MPMCs are very promising carriers for drug delivery systems and magnetic resonance imaging.关键词
蛋白质微胶囊/声化学法/磁性Fe3O4纳米粒子/靶向传输Key words
Protein microcapsule/ Sonochemical method/ Magnetic Fe3O4 nanoparticle/ Targeted delivery分类
化学化工引用本文复制引用
王春蕾,闫俊涛,钟双玲,李占锋,崔学军,王洪艳..磁性蛋白质微胶囊的声化学法构筑[J].高等学校化学学报,2013,34(2):462-466,5.基金项目
国家自然科学基金(批准号:21104023)和教育部博士点新教师基金(批准号:20090061120078)资助. (批准号:21104023)