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磁性蛋白质微胶囊的声化学法构筑

王春蕾 闫俊涛 钟双玲 李占锋 崔学军 王洪艳

高等学校化学学报2013,Vol.34Issue(2):462-466,5.
高等学校化学学报2013,Vol.34Issue(2):462-466,5.DOI:10.7503/cjcu20120639

磁性蛋白质微胶囊的声化学法构筑

Fabrication of Magnetic Protein Microcapsules by Sonochemical Method

王春蕾 1闫俊涛 2钟双玲 1李占锋 2崔学军 3王洪艳1

作者信息

  • 1. 吉林大学化学学院,长春130012
  • 2. 武汉工业学院化学与环境工程学院,武汉430023
  • 3. 吉林农业大学资源与环境学院,长春130118
  • 折叠

摘要

Abstract

Biocompatible magnetic protein microcapsules ( MPMCs) were prepared by sonochemical method. Under high intensity ultrasonic treatment, the MPMCs were yielded at the interface between the oil liquids containing Fe3O4 nanoparticles and the protein solution within several minutes. Meanwhile, the hydrophobic drugs could be loaded into MPMCs directly via sonochemical method and the activities of proteins and drugs were not destroyed. The sonochemical technique is a very simple and cost-effective method to fabricate MPMCs as drug carriers. Such prepared MPMCs are very promising carriers for drug delivery systems and magnetic resonance imaging.

关键词

蛋白质微胶囊/声化学法/磁性Fe3O4纳米粒子/靶向传输

Key words

Protein microcapsule/ Sonochemical method/ Magnetic Fe3O4 nanoparticle/ Targeted delivery

分类

化学化工

引用本文复制引用

王春蕾,闫俊涛,钟双玲,李占锋,崔学军,王洪艳..磁性蛋白质微胶囊的声化学法构筑[J].高等学校化学学报,2013,34(2):462-466,5.

基金项目

国家自然科学基金(批准号:21104023)和教育部博士点新教师基金(批准号:20090061120078)资助. (批准号:21104023)

高等学校化学学报

OA北大核心CSCDCSTPCD

0251-0790

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