摘要
Abstract
Objective: To evaluate the hepatic artery interventional therapy combined with targeted therapy efficacy and adverse drug reactions in the treatment of colon cancer liver metastasis. Method: 78 cases of colon cancer patients with liver metastases were randomly divided into intervention group and control group, intervention group application hepatic artery intervention ( TACE ) combined targeting treatment. Control group were treated with artery interventional therapy ( TACE ). Results: The intervention group and control group response rate was 80. 9% and 55. 6% respectively, the difference was significant ( P <0. 05 ). The survival rate after treatment 0. 5 ,1,2,3,5 years, the intervention group was 94. 3% , 68. 8% , 33. 7% , 18.4% , 10. 3% , the control group was 84. 2% , 54. 6% , 19. 6% , 8.1% , 2. 5%. There was significance different between the two groups ( P <0. 05 ). No significant differences in adverse drug reactions and complications between the two groups. Conclusion: The effect of hepatic artery interventional therapy combined with targeted therapy of colon cancer patients with liver metastases, is superior to simple hepatic artery interventional therapy.关键词
结肠癌肝转移/肝动脉介入治疗/靶向治疗Key words
Colon cancer liver metastases/ Hepatic artery interventional treatment/ Targeted therapy