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肝动脉介入联合靶向治疗结肠癌肝转移临床研究

郑志勇

河北医学2013,Vol.19Issue(4):546-549,4.
河北医学2013,Vol.19Issue(4):546-549,4.DOI:10.3969/j.issn.1006-6233.2013.04.025

肝动脉介入联合靶向治疗结肠癌肝转移临床研究

Research on Hepatic Artery Interventional Therapy Combined with Targeted Therapy for Colon Cancer Liver Metastasis

郑志勇1

作者信息

  • 1. 广西壮族自治区柳州市工人医院,广西,柳州,545005
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摘要

Abstract

Objective: To evaluate the hepatic artery interventional therapy combined with targeted therapy efficacy and adverse drug reactions in the treatment of colon cancer liver metastasis. Method: 78 cases of colon cancer patients with liver metastases were randomly divided into intervention group and control group, intervention group application hepatic artery intervention ( TACE ) combined targeting treatment. Control group were treated with artery interventional therapy ( TACE ). Results: The intervention group and control group response rate was 80. 9% and 55. 6% respectively, the difference was significant ( P <0. 05 ). The survival rate after treatment 0. 5 ,1,2,3,5 years, the intervention group was 94. 3% , 68. 8% , 33. 7% , 18.4% , 10. 3% , the control group was 84. 2% , 54. 6% , 19. 6% , 8.1% , 2. 5%. There was significance different between the two groups ( P <0. 05 ). No significant differences in adverse drug reactions and complications between the two groups. Conclusion: The effect of hepatic artery interventional therapy combined with targeted therapy of colon cancer patients with liver metastases, is superior to simple hepatic artery interventional therapy.

关键词

结肠癌肝转移/肝动脉介入治疗/靶向治疗

Key words

Colon cancer liver metastases/ Hepatic artery interventional treatment/ Targeted therapy

引用本文复制引用

郑志勇..肝动脉介入联合靶向治疗结肠癌肝转移临床研究[J].河北医学,2013,19(4):546-549,4.

河北医学

OACSTPCD

1006-6233

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