化工学报2013，Vol.64Issue(2)：663-670,8.DOI:10.3969/j.issn.0438-1157.2013.02.034
聚丙烯膜表面磷脂自组装/交联改性及其表面性能
Surface modification of polypropylene microporous membrane via self-assembly and UV-crosslinking of lecithin and analysis of surface properties
摘要
Abstract
A novel approach to modification of polypropylene microporous membrane (PPMM) surface based on molecular self-assembly and UV-crosslinking was devised. First, natural amphiphilic lecithin was introduced onto the PPMM surface via self-assembly. Then, a stable biomimetic surface analogy with phospholipid layer was constructed through UV-crosslinking of lecithin, conferring the PPMM surface with good hydrophilicity and biocompatibility. The anchoring of lecithin was confirmed by Fourier transformed infrared spectroscopy/attenuated total reflection (FTIR/ATR) and X-ray photoelectron spectroscopy (XPS) studies. Water contact angle, fluorescence labeled protein (FITC-protein) adsorption,and enzyme-linked immuno-sorbent assay ( ELISA ) were used to evaluate hydrophilicity and biocompatibility of the membrane. Water contact angle of the PPMMs surface was significantly improved after modification, by a decrease from 130° to 30°. Moreover, the modified membranes showed lower protein adsorption. Furthermore, the self-assembly and UV-crosslinking modified membrane exhibited good stability even after multiple washing compared with the self-assembly modified one.关键词
聚丙烯微孔膜/卵磷脂/自组装/紫外交联/生物相容性Key words
polypropylene microporous membrane/lecithin/self-assembly/UV-crosslinking/biocompatibility分类
化学化工引用本文复制引用
王亮,宇海银,何桂金,黄小军..聚丙烯膜表面磷脂自组装/交联改性及其表面性能[J].化工学报,2013,64(2):663-670,8.基金项目
化学工程联合国家重点实验室开放课题项目(SKL-ChE-10D02) （SKL-ChE-10D02）
浙江省新材料及加工工程省重中之重学科开放课题项目(20110915). （20110915）
