湖南中医药大学学报2012，Vol.32Issue(12)：11-12,14,3.DOI:10.3969/j.issn.1674-070X.2012.12.005.011.03
还少丹对D-半乳糖致衰小鼠的抗衰老作用
Research for anti-aging function of huanshaodan in aged mice induced by D-galactose
摘要
Abstract
Objective To investigate the effect and mechanism of huanshaodan on anti-aging in aged mice induced by D-galactose(D-gal). Methods The aged model was established by injecting D-gal. After feeding with huanshaodan for 6 weeks, spectrophotometry was used to detect the activity of glutathione peroxidase and superoxidase dismutase in the brain and liver of mice. Meanwhile the liver index and spleen index of mice were also detected. Results The liver index, spleen index, and the activity of glutathione peroxidase and superoxidase dismutase of brain and liver in the aged model group were significantly reduced, whereas the liver index, spleen index.the activity of superoxidase dismutase and glutathione peroxidase in the brain and liver were elevated remarkably. Conclusion The activity of glutathione peroxidase and superoxidase dismutase in the brain and liver of aged mice can be elevated by huanshaodan, and so do the liver index and spleen index, which suggest that huanshaodan has an anti-aging effect through eliminating free radicals and improving the immunity.关键词
还少丹/D-半乳糖诱导致衰模型/抗氧化Key words
Huanshaodan/Aged model induced by D-galactose/Oxidation resistance分类
医药卫生引用本文复制引用
程莉娟,刘群良,谭峰,张波,陈伶利..还少丹对D-半乳糖致衰小鼠的抗衰老作用[J].湖南中医药大学学报,2012,32(12):11-12,14,3.基金项目
湖南省科技计划一般资助项目(2012FJ4096). （2012FJ4096）
