华侨大学学报（自然科学版）2013，Vol.34Issue(1)：56-58,3.
N-硝基苯甲酰基-1,3,4,6-四-O-乙酰基-2-脱氧-β-D-氨基葡萄糖的合成与表征
Synthesis and Characterization of N-Nitromaticacyl-1,3,4,6-Tetra-O-Acetyl-2-Deoxy-β-D-Glucopyranose
摘要
Abstract
N-nitromaticacyl-l,3,4,6-tetra-O-acetyl-2-deoxy-β-D-glucopyranose was synthesized via D-glucosamine hydrochloride, m-nitrobenzoic acid/p-nitrobenzoic acid and dicyclohexylcarbodiimide (DCC) which was used as dehydration reagent, where D-glucosamine hydrochloride was protected by acetyl group. The products were characterized by Fourier transform infrared spectroscopy (FT-IR), magnetic resonance spectroscopy CH NMR). We concluded the optimal reaction conditions: the molar ratio of N-nitromaticacyl-l,3,4,6-tetra-O-acety-2-deoxy-β-D-glucopyranose, dicyclohexylcarbodiimide and m-nitrobenzoic acid/p-nitrobenzoic acid is 1 : 1. 5 : 1. 5, the temperature is 40 ℃ and the reaction time is 4h.关键词
D-氨基葡萄糖/N-硝基苯甲酰基-1,3,4,6-四-O-乙酰基-2-脱氧-β-D-氨基葡萄糖/N,N-二环已基碳二亚胺/对硝基苯甲酸/间硝基苯甲酸Key words
D-glucosamine hydrochloride/ N-nitromaticacyl-1,3,4,6-tetra-O-acetyl-2-deoxy-β-D- glucopyranose/ dicyclohexylcarbodiimide/ p-nitrobenzoic acid/ m-nitrobenzoic acid分类
化学化工引用本文复制引用
刘玮炜,吴杨全,龚峰,陶传洲,郭维维..N-硝基苯甲酰基-1,3,4,6-四-O-乙酰基-2-脱氧-β-D-氨基葡萄糖的合成与表征[J].华侨大学学报（自然科学版）,2013,34(1):56-58,3.基金项目
江苏省高校自然科学研究重大基金资助项目(10KJA170003) （10KJA170003）
江苏省教育厅自然科学基金资助项目(08KJB150002) （08KJB150002）
江苏省高校科研成果产业化推进项目(JHB2012-60) （JHB2012-60）
江苏省"六大人才高峰"科研基金资助项目(07-A-024) （07-A-024）
江苏省连云港市科技攻关项目(CG1105) （CG1105）
