基础医学与临床2013，Vol.33Issue(1)：9-14,6.
microRNA与肿瘤细胞周期的关系及其研究方法进展
microRNA, cell cycle regulation and its research method
周珏宇 1石嵘 1郑文岭 1马文丽1
作者信息
- 1. 南方医科大学基因工程研究所,广东广州510515
- 折叠
摘要
Abstract
Recent studies have identified specific microRNAs that regulate classic cell-cycle control pathways by directly targeting at proteins such as E2F transcription factors, cyclin-dependent kinases (Cdks) , cyclins and Cdk inhibitors. The loss or gain of miRNA-mediated cell-cycle control contributes to malignancy. This review summarizes experimental strategies for miRNAs research and recent progression on the involvement of miRNAs in cell cycle regulation and tumorigenesis.关键词
miRNA/非编码RNA/癌症/细胞周期/肿瘤发生Key words
miRNA/ non-coding RNA/ cancer/ cell cycle/ tumorigenesis分类
生物科学引用本文复制引用
周珏宇,石嵘,郑文岭,马文丽..microRNA与肿瘤细胞周期的关系及其研究方法进展[J].基础医学与临床,2013,33(1):9-14,6.
