基础医学与临床2013,Vol.33Issue(2):235-238,4.
巨噬细胞源性泡沫细胞胆固醇代谢与动脉粥样硬化
Cholesterol metabolism of macrophage foam cells and atherosclerosis
摘要
Abstract
Foam cells is formed in early stage of atherosclerosis. The transformation of macrophage foam cell involves the disruption of a homeostatic mechanism that controls the uptake, intracellular metabolism and efflux of cholesterol by macrophages. The research of the mechanism of foam cells has a great significance for the prevention and the treatment for the atherosclerosis.关键词
巨噬细胞/清道夫受体/ATP结合盒转运子/酰基辅酶A/胆固醇酰基转移酶/胆固醇酯水解酶Key words
macrophage/ scavenger recptor/ ABC transporter/ ACAT/ CEH分类
医药卫生引用本文复制引用
徐艳杰,程晓曙..巨噬细胞源性泡沫细胞胆固醇代谢与动脉粥样硬化[J].基础医学与临床,2013,33(2):235-238,4.基金项目
"十一五"国家科技支撑计划(2008BA I 68B02) (2008BA I 68B02)