临床肝胆病杂志2013，Vol.29Issue(1)：38-41,4.
磁共振磁敏感加权成像在肝硬化结节多步癌变中的临床应用
Clinical value of susceptibility-weighted imaging for studying the multi-step hepatocarcinogenic process of cirrhotic liver nodules
曾蒙苏 1李若坤2
作者信息
- 1. 复旦大学附属中山医院放射诊断科,上海市影像医学研究所,复旦大学上海医学院影像学系,上海200032
- 2. 复旦大学附属金山医院放射科,上海201508
- 折叠
摘要
Abstract
Early detection, diagnosis, and effective treatment markedly improves the 5-year survival rate of patients with hepatocellular carcinoma ( HCC) . Initiation of the multi-step hepatocarcinogenesis process often involves a cirrhotic nodule. After the regenerative nodule develops into a dysplastic nodule ( DN) , it continues to advance from a low degree DN to a high degree DN. The high degree DN may then further develop to early HCC/small HCC or even progressed/advanced HCC. Previous studies have shown that endogenous iron within the nodule can inhibit or resolve the hepatocarcinogenic process. This review discusses the clinical utility of magnetic resonance ( MR) susceptibility-weighted imaging for detecting and monitoring changes in nodular iron and the implications of this technology when combined with T2WI, diffusion weighted imaging, and dynamic contrast enhancement for improving clinical decision-making, thereby enhancing diagnostic efficacy for early HCC/small HCC in the cirrhotic background.关键词
肝硬化/癌,肝细胞/铁化合物/磁共振成像Key words
liver cirrhosis/ carcinoma, hepatocellular/ iron compounds/ magnetic resonance imaging分类
医药卫生引用本文复制引用
曾蒙苏,李若坤..磁共振磁敏感加权成像在肝硬化结节多步癌变中的临床应用[J].临床肝胆病杂志,2013,29(1):38-41,4.
