临床肝胆病杂志2013，Vol.29Issue(1)：42-44,3.
肝内胆管细胞癌的临床病理学观察
Clinicopathological study of intrahepatic bile duct cancers from 1982 to 2011
朱珍 1丛文铭1
作者信息
- 1. 第二军医大学东方肝胆外科医院病理科,上海200438
- 折叠
摘要
Abstract
Based on tumor histogenesis, intrahepatic bile duct cancers can be classified as intrahepatic cholangiocarcinoma ( ICC ) , cholan-giocellular carcinoma (CLC) , or combined hepatocellular-cholangiocarcinoma ( CHC). ICC is the second most common hepatic malignant tumor type, after hepatocellular carcinoma ( HCC) . Pathological analysis of more than 33 000 malignant liver tumors surgically resected from patients in our hospital between January 1982 and December 2011 revealed that HCC and ICC types accounted for 85. 6% and 7. 7% , respectively. In addition, clinicopathological analyses of these tumors and patient cases revealed an annual increase in incidence of ICC that was accompanied by similar positive trends in metastasis and recurrence. CLC cases were rare, but generally characterized as aggressive and originating from bipotential hepatic progenitor cells. For CHC tumors, there was an increasing trend for the pathological detection rates, but the prognosis of CHC cases remained worse than that for either HCC or ICC. The accumulated data of our institutes cases of intrahepatic bile duct cancers over the past 30 years indicate that pathological classification has important clinical implications for treatment and outcome.关键词
胆管肿瘤/病理学,临床Key words
bile duct neoplasms/ pathology, clinical分类
医药卫生引用本文复制引用
朱珍,丛文铭..肝内胆管细胞癌的临床病理学观察[J].临床肝胆病杂志,2013,29(1):42-44,3.
